遺伝子レベル∞スパイラル (GENE LEVEL ∞ SPIRAL) is a maimai original song composed by NAOKI (Naoki Maeda) featuring vocals by Riyu Kosaka (小坂りゆ). Released on April 1, 2022, as part of maimai DX UNiVERSE PLUS, the track was an April Fools' Day surprise, the game's first such holiday-themed release since 全世界共通リズム感テスト (World Common Rhythm Sense Test). It also marks Kosaka's debut vocal performance in a SEGA arcade music game. The song runs at 164 BPM with a driving electronic arrangement, and its lyrics tell a story of crossing time at a genetic level to reunite with someone destined. The music video carries a piece of SEGA corporate history: it was filmed while SEGA's headquarters were still based near Otorii Station, a location the company moved away from in August 2018. As a result, the video features the original pre-DX maimai cabinet (the white model with the classic rounded logo) rather than the modern DX cabinet. The jacket art likewise uses the old maimai logo, a first for any DX-era original song, following in the visual tradition of earlier tracks like Garakuta Doll Play, VERTeX, and 花と、雪と、ドラムンベース。. According to a one-day-only OMEGA OFFICE top page, the song and video were produced during this "old Otorii era," meaning the track took roughly eight to nine years from production to its in-game debut. 遺伝子レベル∞スパイラル later crossed over to オンゲキ (ONGEKI) bright MEMORY on January 26, 2023, and was rolled out to Asian maimai cabinets on August 5, 2022, and Chinese cabinets (舞萌DX 2023) on July 6, 2023.